I didn't see it mentioned yet, so I'll mention that system builder sites are mostly recommending a 64-bit OS. Reasons vary; I'd do it because I'd like more memory than 32-bit allows.
If you haven't already decided, here's a good summary of differences for Windows: http://support.microsoft.com/kb/946765
If you haven't already decided, here's a good summary of differences for Windows: http://support.microsoft.com/kb/946765
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